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NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively.
Targets
| SHP-2 | SHP-1 | |||
| 318 nM | 355 nM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.86 mL | 99.32 mL | 198.64 mL |
| 0.5 mM | 3.97 mL | 19.86 mL | 39.73 mL |
| 1 mM | 1.99 mL | 9.93 mL | 19.86 mL |
| 5 mM | 0.4 mL | 1.99 mL | 3.97 mL |
*The above data is based on the productmolecular weight 503.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16120 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 503.42 |
| Formula | C19H13N3O7S2.2Na |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 56932-43-5 |
| Synonyms | NSC-87877, NSC 87877 |
| SMILES | C1=CC2=C(C(=O)C(=NNC3=CC4=C(C=C3)C=C(C=C4)S(=O)(=O)[O-])C=C2S(=O)(=O)[O-])N=C1.[Na+].[Na+] |
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