NT160

Catalog No.: A24059
class-IIa HDAC inhibitor
NT160 is a highly potent inhibitor of class IIa histone deacetylases (HDACs), with an IC₅₀ value of 0.046 μM. Due to its strong inhibitory activity and potential central nervous system (CNS) penetration, NT160 is a valuable compound for investigating the role of class IIa HDACs in CNS-related disorders, including neurodegenerative and neuropsychiatric diseases.
Grouped product items
Size Price Stock Qty
5mg
$252.00
In stock
10mg
$434.00
In stock
50mg
$1,288.00
In stock
100mg
$2,520.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNT160 is a highly potent inhibitor of class IIa histone deacetylases (HDACs), with an IC₅₀ value of 0.046 μM. Due to its strong inhibitory activity and potential central nervous system (CNS) penetration, NT160 is a valuable compound for investigating the role of class IIa HDACs in CNS-related disorders, including neurodegenerative and neuropsychiatric diseases.
Product Information
Catalog NumA24059
FormulaC21H21F3N4O2
Molecular Weight418.41
CAS Number1418293-40-9
SMILESO=C(N[C@H](C)CN(CC1=CC=CC=C1)C)C2=CC=C(C=C2)C3=NOC(C(F)(F)F)=N3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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