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MGCD0103 (Mocetinostat)

HDAC Inhibitor

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Catalog No. A10586

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
MGCD0103 5mg A10586-5
MGCD0103 10mg A10586-10
MGCD0103 25mg A10586-25
MGCD0103 50mg A10586-50
MGCD0103 (Mocetinostat) 10mM * 1mL in DMSO A10586-10mM-D

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

MGCD0103 (Mocetinostat) is a benzamide histone deacetylase inhibitor by inhibiting mainly histone deacetylase 1 (HDAC1), but also HDAC2, HDAC3, and HDAC11.

MGCD0103 (Mocetinostat)

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Publications citing Adooq Products
MGCD0103 (Mocetinostat) Citations (2)
  • Mari Ishigami-Yuasa, .et al. Class IIb HDAC Inhibition Enhances the Inhibitory Effect of Am80, a Synthetic Retinoid, in Prostate Cancer, Biol Pharm Bull, 2019, 42, 448-452
  • Guang Bai, .et al. Chapter 1 - Epigenetic Tools in Chronic Pain Studies, Epigenetics of Chronic Pain, 2019, Pages 1-48

Chemical Information

Catalog Num A10586
Actions Inhibitor
M. Wt 396.4
Formula C23H20N6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 726169-73-9
Synonyms MGCD-0103

Biological Activity

MGCD0103 (Mocetinostat) is a benzamide histone deacetylase inhibitor by inhibiting mainly histone deacetylase 1 (HDAC1), but also HDAC2, HDAC3, and HDAC11.
Target Value
HDAC1IC50: 0.15μM
HDAC2IC50: 0.29μM
HDAC11IC50: 0.59μM
HDAC3IC50: 1.66μM
HDAC4IC50: >10μM
HDAC5IC50: >10μM
HDAC6IC50: >10μM
HDAC7IC50: >10μM
HDAC8IC50: >10μM


Solubility (25°C) * In vitro DMSO 13 mg/mL (32.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.23 mL 126.14 mL 252.27mL
0.5 mM 5.05 mL 25.23 mL 50.45 mL
1 mM 2.52 mL 12.61 mL 25.23 mL
5 mM 0.5 mL 2.52 mL 5.05 mL

*The above data is based on the productmolecular weight 396.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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