MGCD0103 (Mocetinostat)

Catalog No.: A10586

HDAC Inhibitor

MGCD0103 (Mocetinostat)

MGCD0103 (Mocetinostat) Chemical Structure

CAS NO. 726169-73-9

MGCD0103 (Mocetinostat) is a benzamide histone deacetylase inhibitor by inhibiting mainly histone deacetylase 1 (HDAC1), but also HDAC2, HDAC3, and HDAC11.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $40.00

Special Price $32.00

10 mg

Regular Price: $50.00

Special Price $40.00

25 mg

Regular Price: $70.00

Special Price $56.00

50 mg

Regular Price: $99.00

Special Price $79.20

10mM * 1mL in DMSO
$55.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

MGCD0103 (Mocetinostat) is a benzamide histone deacetylase inhibitor by inhibiting mainly histone deacetylase 1 (HDAC1), but also HDAC2, HDAC3, and HDAC11.
Targets
Target Value
HDAC1IC50: 0.15μM
HDAC2IC50: 0.29μM
HDAC11IC50: 0.59μM
HDAC3IC50: 1.66μM
HDAC4IC50: >10μM
HDAC5IC50: >10μM
HDAC6IC50: >10μM
HDAC7IC50: >10μM
HDAC8IC50: >10μM
In vitro (25°C) DMSO 13 mg/mL (32.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.23 mL 126.14 mL 252.27 mL
0.5 mM 5.05 mL 25.23 mL 50.45 mL
1 mM 2.52 mL 12.61 mL 25.23 mL
5 mM 0.5 mL 2.52 mL 5.05 mL

*The above data is based on the productmolecular weight 396.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10586
Actions Inhibitor
M. Wt 396.4
Formula C23H20N6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 726169-73-9
Synonyms MGCD-0103
SMILES C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC3=NC=CC(=N3)C4=CN=CC=C4

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