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$0.00 Biological Activity
MGCD0103 (Mocetinostat) is a benzamide histone deacetylase inhibitor by inhibiting mainly histone deacetylase 1 (HDAC1), but also HDAC2, HDAC3, and HDAC11.
Targets
| Target | Value |
|---|---|
| HDAC1 | IC50: 0.15μM |
| HDAC2 | IC50: 0.29μM |
| HDAC11 | IC50: 0.59μM |
| HDAC3 | IC50: 1.66μM |
| HDAC4 | IC50: >10μM |
| HDAC5 | IC50: >10μM |
| HDAC6 | IC50: >10μM |
| HDAC7 | IC50: >10μM |
| HDAC8 | IC50: >10μM |
| In vitro (25°C) | DMSO | 13 mg/mL (32.79 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
| In vivo | 30% PEG400/0.5% Tween80/5% propylene glycol | 30 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.23 mL | 126.14 mL | 252.27 mL |
| 0.5 mM | 5.05 mL | 25.23 mL | 50.45 mL |
| 1 mM | 2.52 mL | 12.61 mL | 25.23 mL |
| 5 mM | 0.5 mL | 2.52 mL | 5.05 mL |
*The above data is based on the productmolecular weight 396.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10586 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 396.4 |
| Formula | C23H20N6O |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 726169-73-9 |
| Synonyms | MGCD-0103 |
| SMILES | C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC3=NC=CC(=N3)C4=CN=CC=C4 |
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