Nurandociguatum

Catalog No.: A60886
Guanylate Cyclase Activator
Nurandociguatum is a guanylate cyclase activator that enhances intracellular cGMP levels, leading to vasodilation and modulation of nitric oxide signaling. This compound is primarily utilized in cardiovascular research, particularly in studies investigating pulmonary hypertension and heart failure mechanisms. Its ability to stimulate guanylate cyclase makes it a valuable tool for exploring therapeutic strategies targeting vascular relaxation and nitric oxide pathways.
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Size Stock
5mg
10mg
50mg
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Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNurandociguatum is a guanylate cyclase activator that enhances intracellular cGMP levels, leading to vasodilation and modulation of nitric oxide signaling. This compound is primarily utilized in cardiovascular research, particularly in studies investigating pulmonary hypertension and heart failure mechanisms. Its ability to stimulate guanylate cyclase makes it a valuable tool for exploring therapeutic strategies targeting vascular relaxation and nitric oxide pathways.
Product Information
Catalog NumA60886
FormulaC30H36ClF2N5O2
Molecular Weight572.09
CAS Number2781965-75-9
SMILESClC1=CC(N2C[C@H](N3C(C(F)F)=C(C=N3)C(O)=O)CCC2)=C(C4=CC=C(N5CCN(CC5)CC(C)C)C=C4)C=C1
SynonymsNurandociguat
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