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Nurandociguatum

Guanylate Cyclase Activator

Nurandociguatum is a guanylate cyclase activator that enhances intracellular cGMP levels, leading to vasodilation and modulation of nitric oxide signaling. This compound is primarily utilized in cardiovascular research, particularly in studies investigating pulmonary hypertension and heart failure mechanisms. Its ability to stimulate guanylate cyclase makes it a valuable tool for exploring therapeutic strategies targeting vascular relaxation and nitric oxide pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Activator
CAS Number	2781965-75-9
Applications	Guanylate Cyclase Activator
Formula	C₃₀H₃₆ClF₂N₅O₂
Molecular Weight	572.09
Synonyms	Nurandociguat
SMILES	ClC1=CC(N2C[C@H](N3C(C(F)F)=C(C=N3)C(O)=O)CCC2)=C(C4=CC=C(N5CCN(CC5)CC(C)C)C=C4)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.