NVP-BSK805 dihydrochloride
Important Notice: For research use only. We do not sell to patients.
Other Forms of NVP-BSK805 dihydrochloride
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Important Notice: For research use only. We do not sell to patients.
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Discription | NVP-BSK805 dihydrochloride (BSK805 dihydrochloride) is an ATP-competitive JAK2 inhibitor, with IC50s of 0.48 nM, 31.63 nM, 18.68 nM, and 10.76 nM for JAK2 JH1 (JAK homology 1), JAK1 JH1, JAK3 JH1, and TYK2 JH1, respectively. | ||
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Catalog Num | A21406 |
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Formula | C27H30Cl2F2N6O |
Molecular Weight | 563.47 |
CAS Number | 1942919-79-0 |
SMILES | FC1=C(CN2CCOCC2)C(F)=CC(C3=C4N=C(C5=CN(C6CCNCC6)N=C5)C=NC4=CC=C3)=C1.Cl.Cl |
Synonyms | BSK805 dihydrochloride, BSK 805, BSK-805 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 104 mg/mL (184.57 mM) | |
Water | 3 mg/mL (5.32 mM) | ||
Ethanol | 14 mg/mL (24.85 mM) | ||
In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 17.75 mL | 88.74 mL | 177.47 mL |
0.5 mM | 3.55 mL | 17.75 mL | 35.49 mL |
1 mM | 1.77 mL | 8.87 mL | 17.75 mL |
5 mM | 0.35 mL | 1.77 mL | 3.55 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2