NVP-BSK805 dihydrochloride

Catalog No.: A21406

JAK2 inhibitor

NVP-BSK805 dihydrochloride

NVP-BSK805 dihydrochloride Chemical Structure

CAS NO. 1942919-79-0

NVP-BSK805 dihydrochloride (BSK805 dihydrochloride) is an ATP-competitive JAK2 inhibitor, with IC50s of 0.48 nM, 31.63 nM, 18.68 nM, and 10.76 nM for JAK2 JH1 (JAK homology 1), JAK1 JH1, JAK3 JH1, and TYK2 JH1, respectively.

Availability: In stock

Package Price Qty
5 mg
$151.00
10 mg
$260.00
50 mg
$773.00
100 mg
$1,546.00
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Biological Activity

NVP-BSK805 dihydrochloride (BSK805 dihydrochloride) is an ATP-competitive JAK2 inhibitor, with IC50s of 0.48 nM, 31.63 nM, 18.68 nM, and 10.76 nM for JAK2 JH1 (JAK homology 1), JAK1 JH1, JAK3 JH1, and TYK2 JH1, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.75 mL 88.74 mL 177.47 mL
0.5 mM 3.55 mL 17.75 mL 35.49 mL
1 mM 1.77 mL 8.87 mL 17.75 mL
5 mM 0.35 mL 1.77 mL 3.55 mL

*The above data is based on the productmolecular weight 563.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21406
Actions Inhibitor
M. Wt 563.47
Formula C27H30Cl2F2N6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1942919-79-0
Synonyms BSK805 dihydrochloride, BSK 805, BSK-805
SMILES FC1=C(CN2CCOCC2)C(F)=CC(C3=C4N=C(C5=CN(C6CCNCC6)N=C5)C=NC4=CC=C3)=C1.Cl.Cl

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