O-Desmethyl Galanthamine

Catalog No.: A78603
AChE Inhibitor
O-Desmethyl Galanthamine is an acetylcholinesterase (AChE) inhibitor with an IC50 of 1.83 μM. As a galanthamine-type alkaloid, it effectively modulates cholinergic signaling by preventing the breakdown of acetylcholine. This compound is primarily utilized in research focused on neurodegenerative diseases, including Alzheimer's disease, where AChE inhibition is of therapeutic interest.
Grouped product items
Size Price Stock Qty
1mg
$40.00
In stock
5mg
$100.00
In stock
10mg
$165.00
In stock
25mg
$380.00
In stock
50mg
$645.00
In stock
100mg
$855.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionO-Desmethyl Galanthamine is an acetylcholinesterase (AChE) inhibitor with an IC50 of 1.83 μM. As a galanthamine-type alkaloid, it effectively modulates cholinergic signaling by preventing the breakdown of acetylcholine. This compound is primarily utilized in research focused on neurodegenerative diseases, including Alzheimer's disease, where AChE inhibition is of therapeutic interest.
Product Information
Catalog NumA78603
FormulaC16H19NO3
Molecular Weight273.33
CAS Number60755-80-8
SMILESOC1=CC=C2C3=C1O[C@@]4([H])C[C@@H](O)C=C[C@@]34CCN(C)C2
SynonymsSanguinine
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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