O-Desmethyl-N-deschlorobenzoyl Indomethacin is a metabolite of the non-steroidal anti-inflammatory drug indomethacin, acting as a cyclooxygenase (COX) inhibitor. This compound demonstrates significant biological activity by reducing the viability of HL-60 leukemia cells in the presence of glucose oxidase at a concentration of 600 μM. It serves as a valuable reagent in research focused on synthesizing prostaglandin D2 receptor antagonists and elucidating the metabolic pathways of NSAIDs.
O-Desmethyl-N-deschlorobenzoyl Indomethacin is a metabolite of the non-steroidal anti-inflammatory drug indomethacin, acting as a cyclooxygenase (COX) inhibitor. This compound demonstrates significant biological activity by reducing the viability of HL-60 leukemia cells in the presence of glucose oxidase at a concentration of 600 μM. It serves as a valuable reagent in research focused on synthesizing prostaglandin D2 receptor antagonists and elucidating the metabolic pathways of NSAIDs.
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