Fig. 1 · Structure
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o,p'-DDE
Insecticide
o,p'-DDE (2,4-Dichlorodiphenyldichloroethylene) primarily targets the endocrine system as a metabolite of the organochlorine insecticide DDT. It is recognized for its role as a persistent organic pollutant (POP) that accumulates in aquatic organisms and sediments. o,p'-DDE effectively inhibits estrogen binding to the rainbow trout estrogen receptor (rtER) with an IC50 of 3.2 μM and stimulates estradiol secretion in porcine granulosa and theca cell co-cultures. Additionally, in ovo exposure to o,p'-DDE leads to follicular degeneration and decreased testis size in Japanese medaka (Oryzias latipes), making it relevant for studies on endocrine disruption in aquatic species.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 3424-82-6 |
| Applications | Insecticide |
| Formula | C14H8Cl4 |
| Molecular Weight | 318.03 |
| Synonyms | 2,4'-DDE; 2,4-Dichlorodiphenyldichloroethylene; o,p'-Dichlorodiphenyldichloroethylene |
| SMILES | ClC1=CC=C(C=C1)/C(C2=CC=CC=C2Cl)=C(Cl)/Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.