O6BTG-octylglucoside

Catalog No.: A11432

MGMT inhibitor

O6BTG-octylglucoside

O6BTG-octylglucoside Chemical Structure

CAS NO. 382607-78-5

O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells.

Availability: In stock

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5 mg

Regular Price: $315.00

Special Price $252.00

10 mg

Regular Price: $543.00

Special Price $434.40

50 mg

Regular Price: $1,610.00

Special Price $1,288.00

100 mg

Regular Price: $3,220.00

Special Price $2,576.00

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Biological Activity

O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.22 mL 81.1 mL 162.2 mL
0.5 mM 3.24 mL 16.22 mL 32.44 mL
1 mM 1.62 mL 8.11 mL 16.22 mL
5 mM 0.32 mL 1.62 mL 3.24 mL

*The above data is based on the productmolecular weight 616.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11432
Actions Inhibitor
CAS No. 382607-78-5
Formula C24H34BrN5O7S
M. Wt 616.53
Purity >98%
Synonyms Glucose-conjugated MGMT inhibitor
SMILES [H][[email protected]]1([[email protected]]([H])(O[[email protected]@](OCCCCCCCCN2C3=C(N=C2)C(OCC4=CC(Br)=CS4)=NC(N)=N3)([[email protected]](O)([[email protected]]1(O)[H])[H])[H])CO)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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