O6BTG-octylglucoside

Catalog No.: A11432

MGMT inhibitor

O6BTG-octylglucoside

O6BTG-octylglucoside Chemical Structure

CAS NO. 382607-78-5

O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells.

Availability: In stock

Package Price Qty
5 mg
$315.00
10 mg
$543.00
50 mg
$1,610.00
100 mg
$3,220.00
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Biological Activity

O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.22 mL 81.1 mL 162.2 mL
0.5 mM 3.24 mL 16.22 mL 32.44 mL
1 mM 1.62 mL 8.11 mL 16.22 mL
5 mM 0.32 mL 1.62 mL 3.24 mL

*The above data is based on the productmolecular weight 616.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11432
Actions Inhibitor
M. Wt 616.53
Formula C24H34BrN5O7S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 382607-78-5
Synonyms Glucose-conjugated MGMT inhibitor
SMILES [H][[email protected]]1([[email protected]]([H])(O[[email protected]@](OCCCCCCCCN2C3=C(N=C2)C(OCC4=CC(Br)=CS4)=NC(N)=N3)([[email protected]](O)([[email protected]]1(O)[H])[H])[H])CO)O

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