ODE-Bn-PMEG is an antiviral compound that targets human papillomavirus (HPV) by inhibiting the amplification of viral DNA. Demonstrating robust activity against HPV-11, -16, and -18, ODE-Bn-PMEG effectively reduces transient viral replication in transfected cells without reaching cytotoxic levels. The compound exhibits enhanced uptake in human foreskin fibroblasts and is converted to the active antiviral metabolite PMEG diphosphate in vitro. Additionally, the P-chiral enantiomer of ODE-Bn-PMEG maintains comparable antiviral efficacy, highlighting its potential for use against multiple HPV strains and in local therapeutic applications.
ODE-Bn-PMEG is an antiviral compound that targets human papillomavirus (HPV) by inhibiting the amplification of viral DNA. Demonstrating robust activity against HPV-11, -16, and -18, ODE-Bn-PMEG effectively reduces transient viral replication in transfected cells without reaching cytotoxic levels. The compound exhibits enhanced uptake in human foreskin fibroblasts and is converted to the active antiviral metabolite PMEG diphosphate in vitro. Additionally, the P-chiral enantiomer of ODE-Bn-PMEG maintains comparable antiviral efficacy, highlighting its potential for use against multiple HPV strains and in local therapeutic applications.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
