Okicenone

Catalog No.: A57792
HuR Inhibitor
Okicenone is an inhibitor of Hu protein R (HuR), a key regulator of messenger RNA stability and translation. By disrupting HuR oligomerization and its RNA binding capabilities, Okicenone modulates HuR trafficking, influencing cytokine expression and T-cell activation. This compound is valuable in research focused on immune response modulation and the role of mRNA-binding proteins in cellular processes.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionOkicenone is an inhibitor of Hu protein R (HuR), a key regulator of messenger RNA stability and translation. By disrupting HuR oligomerization and its RNA binding capabilities, Okicenone modulates HuR trafficking, influencing cytokine expression and T-cell activation. This compound is valuable in research focused on immune response modulation and the role of mRNA-binding proteins in cellular processes.
Product Information
Catalog NumA57792
FormulaC15H14O4
Molecular Weight258.27
CAS Number137018-54-3
SMILESO=C1CCC(O)C2=C1C(O)=C3C(C)=CC(O)=CC3=C2
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