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Olcegepant is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and Ki of 14.4 pM for human CGRP.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 11.5 mL | 57.49 mL | 114.99 mL |
| 0.5 mM | 2.3 mL | 11.5 mL | 23 mL |
| 1 mM | 1.15 mL | 5.75 mL | 11.5 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
*The above data is based on the productmolecular weight 869.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11512 |
|---|---|
| CAS No. | 204697-65-4 |
| Formula | C38H47Br2N9O5 |
| M. Wt | 869.65 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | BIBN-4096; BIBN 4096BS |
| SMILES | O=C1N(CC2=C(N1)C=CC=C2)C3CCN(C(N[[email protected]@H](C(N[[email protected]](C(N4CCN(C5=CC=NC=C5)CC4)=O)CCCCN)=O)CC6=CC(Br)=C(C(Br)=C6)O)=O)CC3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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