Oleanonic acid, a triterpene, primarily targets anti-HIV activity. It exhibits notable anti-inflammatory properties and can ameliorate conditions associated with oxidative stress, autophagy dysfunction, ferroptosis, mitochondrial damage, and endoplasmic reticulum stress, particularly induced by Amyloid-β in vitro. Additionally, oleanonic acid has been demonstrated to reduce myocardial hypertrophy in rat models in vivo, highlighting its potential for therapeutic applications in cardiovascular and neurodegenerative research.
Oleanonic acid, a triterpene, primarily targets anti-HIV activity. It exhibits notable anti-inflammatory properties and can ameliorate conditions associated with oxidative stress, autophagy dysfunction, ferroptosis, mitochondrial damage, and endoplasmic reticulum stress, particularly induced by Amyloid-β in vitro. Additionally, oleanonic acid has been demonstrated to reduce myocardial hypertrophy in rat models in vivo, highlighting its potential for therapeutic applications in cardiovascular and neurodegenerative research.
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