Fig. 1 · Structure
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Oleic Acid-2,6-diisopropylanilide
Cat. No.
A74352
CAS
140112-65-8
Endogenous Metabolite
Oleic Acid-2,6-diisopropylanilide is a potent inhibitor of acylCoA:cholesterol acyltransferase (ACAT), a key enzyme involved in the synthesis of cholesteryl esters related to dietary cholesterol absorption, with an IC50 of 7 nM. This compound has demonstrated biological activity by lowering low-density lipoproteins and increasing high-density lipoprotein levels in animal models subjected to high-fat, high-cholesterol diets. It serves as a valuable tool in research applications focused on lipid metabolism and cardiovascular disease.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 140112-65-8 |
| Applications | Endogenous Metabolite |
| Formula | C30H51NO |
| Molecular Weight | 441.73 |
| SMILES | CC(C1=C(C(C(C)C)=CC=C1)N(C(CCCCCCC/C=C\CCCCCCCC)=O)[H])C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.