Oleic Acid-2,6-diisopropylanilide is a potent inhibitor of acylCoA:cholesterol acyltransferase (ACAT), a key enzyme involved in the synthesis of cholesteryl esters related to dietary cholesterol absorption, with an IC50 of 7 nM. This compound has demonstrated biological activity by lowering low-density lipoproteins and increasing high-density lipoprotein levels in animal models subjected to high-fat, high-cholesterol diets. It serves as a valuable tool in research applications focused on lipid metabolism and cardiovascular disease.
Oleic Acid-2,6-diisopropylanilide is a potent inhibitor of acylCoA:cholesterol acyltransferase (ACAT), a key enzyme involved in the synthesis of cholesteryl esters related to dietary cholesterol absorption, with an IC50 of 7 nM. This compound has demonstrated biological activity by lowering low-density lipoproteins and increasing high-density lipoprotein levels in animal models subjected to high-fat, high-cholesterol diets. It serves as a valuable tool in research applications focused on lipid metabolism and cardiovascular disease.
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