Olsutamig is a bivalent humanized IgG4κ monoclonal antibody that targets FOLH1/PSMA and CD3E. This reagent effectively binds to the prostate-specific membrane antigen (PSMA) on tumor cells and to CD3E on T cells, leading to significant T cell activation. Olsutamig is primarily employed in research focused on immuno-oncology, particularly for its potential to selectively induce apoptosis in prostate cancer cells through T cell-mediated mechanisms.
Olsutamig is a bivalent humanized IgG4κ monoclonal antibody that targets FOLH1/PSMA and CD3E. This reagent effectively binds to the prostate-specific membrane antigen (PSMA) on tumor cells and to CD3E on T cells, leading to significant T cell activation. Olsutamig is primarily employed in research focused on immuno-oncology, particularly for its potential to selectively induce apoptosis in prostate cancer cells through T cell-mediated mechanisms.
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