ON 146040
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | ON 146040 is the first dual PI3K and BCR-ABL inhibitor that targets the STAT3 and STAT5 pathways; inhibits PI3K α/δ isoforms with IC50 of 14/20 nM. | ||
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Catalog Num | A16266 |
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Formula | C24H23N7O3S |
Molecular Weight | 489.55 |
CAS Number | 1404231-34-0 |
SMILES | O=C(NC(C=NC(NC1=CC=C(N2CCN(C)CC2)C=C1)=N3)=C3S/4)C4=C\C5=CC=C([N+]([O-])=O)C=C5 |
Synonyms | ON-146040, ON146040 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2