Ono 3307 free base is a synthetic protease inhibitor that targets kallikrein and other serine proteases. It demonstrates protective effects against acute pancreatitis by inhibiting hyperamylasemia and pancreatic edema, while also reducing cathepsin B leakage from lysosomes in a dose-dependent manner. This compound has significant applications in research related to protease regulation and pancreatic function, making it valuable for studies exploring the pathophysiology of acute pancreatitis and related conditions.
Ono 3307 free base is a synthetic protease inhibitor that targets kallikrein and other serine proteases. It demonstrates protective effects against acute pancreatitis by inhibiting hyperamylasemia and pancreatic edema, while also reducing cathepsin B leakage from lysosomes in a dose-dependent manner. This compound has significant applications in research related to protease regulation and pancreatic function, making it valuable for studies exploring the pathophysiology of acute pancreatitis and related conditions.
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