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ONO 3708

TXA2/PGH2 Receptor Antagonist

ONO 3708 is a selective antagonist of the TXA2/PGH2 receptor, effectively inhibiting the binding of U46619 to human platelets with an IC50 value of 38 nM. This compound is valuable for research into platelet activation and thrombus formation, making it applicable in studies focused on cardiovascular diseases and coagulation processes. Its specificity allows for detailed investigation of TXA2 signaling pathways and their implications in various physiological and pathological conditions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	102191-05-9
Applications	TXA2/PGH2 Receptor Antagonist
Formula	C₂₃H₃₇NO₄
Molecular Weight	391.54
SMILES	OC(CCC/C=C\C[C@H]1[C@H](C2)C(C)([C@H]2C[C@@H]1NC([C@@H](C3CCCC3)O)=O)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.