ONO-8711 is a selective competitive antagonist of the EP1 receptor, with Ki values of 0.6 nM for human and 1.7 nM for mouse EP1. This compound has demonstrated significant efficacy in reducing tumor incidence and multiplicity in mouse models of colon, breast, and oral cancers. ONO-8711 is valuable for research applications related to cancer biology and the modulation of EP1 receptor signaling pathways.
ONO-8711 is a selective competitive antagonist of the EP1 receptor, with Ki values of 0.6 nM for human and 1.7 nM for mouse EP1. This compound has demonstrated significant efficacy in reducing tumor incidence and multiplicity in mouse models of colon, breast, and oral cancers. ONO-8711 is valuable for research applications related to cancer biology and the modulation of EP1 receptor signaling pathways.
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