ONO-AE3-208 sodium salt is a selective antagonist of the EP4 receptor, exhibiting a Ki value of 1.3 nM, which demonstrates its strong binding affinity. This compound has minimal effect on EP3, FP, and TP receptors, with Ki values of 30 nM, 790 nM, and 2400 nM, respectively. ONO-AE3-208 sodium salt has shown significant biological activity in inhibiting cell invasion, migration, and metastasis in prostate cancer research applications.
ONO-AE3-208 sodium salt is a selective antagonist of the EP4 receptor, exhibiting a Ki value of 1.3 nM, which demonstrates its strong binding affinity. This compound has minimal effect on EP3, FP, and TP receptors, with Ki values of 30 nM, 790 nM, and 2400 nM, respectively. ONO-AE3-208 sodium salt has shown significant biological activity in inhibiting cell invasion, migration, and metastasis in prostate cancer research applications.
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