OPC-14523 hydrochloride is a potent agonist of the 5-HT1A receptor, exhibiting high affinity for sigma receptors (σ1/2 IC50=47/56 nM) and the serotonin transporter (IC50=80 nM). This compound demonstrates notable antidepressant-like activity and is valuable for research into mood disorders and neuropharmacology. Its pharmacological profile makes it a useful tool for studies investigating the role of serotonin receptors in depression and anxiety.
OPC-14523 hydrochloride is a potent agonist of the 5-HT1A receptor, exhibiting high affinity for sigma receptors (σ1/2 IC50=47/56 nM) and the serotonin transporter (IC50=80 nM). This compound demonstrates notable antidepressant-like activity and is valuable for research into mood disorders and neuropharmacology. Its pharmacological profile makes it a useful tool for studies investigating the role of serotonin receptors in depression and anxiety.
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