Fig. 1 · Structure

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Opipramol

Sigma (σ) Receptor Agonist

Opipramol is a sigma (σ) receptor agonist that exhibits potent interaction with sigma recognition sites, demonstrating a Ki value of 50 nM. This atypical tricyclic antidepressant (TCA) is primarily utilized in research focused on generalized anxiety disorder (GAD). Its mechanism of action may contribute to modulating anxiety-related behaviors, making it a valuable compound for studies investigating novel therapeutic approaches in anxiety disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 315-72-0
Applications Sigma (σ) Receptor Agonist
Formula C23H29N3O
Molecular Weight 363.50
Synonyms Ensidon; G-33040
SMILES
OCCN1CCN(CCCN2C3=CC=CC=C3C=CC4=CC=CC=C42)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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