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Fig. 1 · Structure
Cat. No.
A29471
CAS No.
210821-63-9
Formula
C10H12Cl2F3N3
Mol. Weight
302.12

Documents & Downloads

Org-12962 hydrochloride

panic, antiaversive, brain, barrier, permeability, BBB

Org-12962 hydrochloride is a selective agonist of the 5-HT2C receptor, demonstrating pEC50 values of 7.01, 6.38, and 6.28 for the 5-HT2C, 5-HT2A, and 5-HT2B receptors, respectively. This compound shows significant efficacy in models of panic-like anxiety, making it valuable for studying anxiety disorders and the underlying mechanisms of the blood-brain barrier permeability. Its application in research enhances understanding of serotonergic pathways in the brain and their implications for anxiety-related conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 210821-63-9
Applications panic, antiaversive, brain, barrier, permeability, BBB
Formula C10H12Cl2F3N3
Molecular Weight 302.12
SMILES
FC(C1=C(Cl)N=C(N2CCNCC2)C=C1)(F)F.[H]Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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