Org-12962 is a selective agonist of the 5-HT2C receptor, demonstrating a pEC50 value of 7.01. In addition to its primary target, Org-12962 shows significant efficacy for the 5-HT2A and 5-HT2B receptors with pEC50 values of 6.38 and 6.28, respectively. This compound is notable for its anti-aversive effects observed in rat models of panic-like anxiety, making it a valuable tool for investigating anxiety disorders and related neuropharmacology.
Org-12962 is a selective agonist of the 5-HT2C receptor, demonstrating a pEC50 value of 7.01. In addition to its primary target, Org-12962 shows significant efficacy for the 5-HT2A and 5-HT2B receptors with pEC50 values of 6.38 and 6.28, respectively. This compound is notable for its anti-aversive effects observed in rat models of panic-like anxiety, making it a valuable tool for investigating anxiety disorders and related neuropharmacology.
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