Fig. 1 · Structure
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Org-24598
GlyT-1 Inhibitor
Org-24598 is a potent inhibitor of glycine transporter 1 (GlyT-1). It effectively inhibits the binding of [3H] CHIBIA-3007 to rat brain membranes, demonstrating a Ki value of 16.9 nM. This compound is valuable for investigating the role of GlyT-1 in neurological disorders and could aid in the development of therapeutics targeting glycine transport.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 372198-97-5 |
| Applications | GlyT-1 Inhibitor |
| Formula | C19H20F3NO3 |
| Molecular Weight | 367.36 |
| SMILES | CN(CC(O)=O)CC[C@@H](OC1=CC=C(C(F)(F)F)C=C1)C2=CC=CC=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.