ORM-10921 free base

Catalog No.: A58241
α-2C Adrenergic Receptor Antagonist
ORM-10921 free base is a selective antagonist of the α-2C adrenergic receptor, exhibiting a Ki value of 1.4 nM. This compound demonstrates significant antidepressant and antipsychotic-like activities, making it a valuable tool for research in neuropharmacology and the exploration of mood disorders. Its specificity and potency position ORM-10921 free base as a potential candidate for studies related to the modulation of neurotransmitter systems.
Grouped product items
Size Price Stock Qty
1mg
$320.00
In stock
5mg
$795.00
In stock
10mg
$1,085.00
In stock
25mg
$1,640.00
In stock
50mg
$2,150.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionORM-10921 free base is a selective antagonist of the α-2C adrenergic receptor, exhibiting a Ki value of 1.4 nM. This compound demonstrates significant antidepressant and antipsychotic-like activities, making it a valuable tool for research in neuropharmacology and the exploration of mood disorders. Its specificity and potency position ORM-10921 free base as a potential candidate for studies related to the modulation of neurotransmitter systems.
Product Information
Catalog NumA58241
FormulaC18H23NO2
Molecular Weight285.38
CAS Number610782-82-6
SMILESC[C@@]1(CCCN2CCC3=C([C@]12[H])OC4=CC=CC=C43)COC
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