ORN 02

Catalog No.: A35430
TLR8 Activator
ORN 02 is a synthetic single-stranded U-rich RNA that acts as a Toll-like receptor 8 (TLR8) activator. This reagent consists of six repeats of the UUAU sequence motif, which enhances its ability to stimulate TLR8 signaling. ORN 02 is useful in research applications focused on immune response modulation and the study of RNA-based therapeutics. Its role in TLR8 activation positions it as an important tool for investigating innate immunity and potential therapeutic strategies.
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5mg
10mg
50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionORN 02 is a synthetic single-stranded U-rich RNA that acts as a Toll-like receptor 8 (TLR8) activator. This reagent consists of six repeats of the UUAU sequence motif, which enhances its ability to stimulate TLR8 signaling. ORN 02 is useful in research applications focused on immune response modulation and the study of RNA-based therapeutics. Its role in TLR8 activation positions it as an important tool for investigating innate immunity and potential therapeutic strategies.
Product Information
Catalog NumA35430
CAS Number937769-72-7
SMILES[ORN 02]
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