Fig. 1 · Structure
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Orotic acid zinc
Active Compound
Orotic acid zinc acts as an active compound involved in the biosynthesis of pyrimidine nucleotides and RNA. It is released as a product from mitochondrial dihydroorotate dehydrogenase (DHODH) and subsequently converted to UMP by UMP synthase in the cytoplasm. This compound is utilized as a biomarker in newborn screening for urea cycle disorders and has been shown to induce hepatic steatosis and hepatomegaly in rodent models, making it relevant for studies in metabolic and liver disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 68399-76-8 |
| Applications | Active Compound |
| Formula | C5H4N2O4Zn0.5 |
| Molecular Weight | 188.79 |
| Synonyms | 6-Carboxyuracil zinc; Vitamin B13 zinc |
| SMILES | O=C(C(NC1=O)=CC(N1)=O)O.[0.5Zn] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.