Drug Derivative

Cat. No.

A25665

CAS No.

2699713-95-4

rel-Latanoprost acid

rel-Latanoprost acid is a relative configuration of Latanoprost acid. Latanoprost acid, an analog of prostaglandin (PG) F2α, is an selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor. Latanoprost acid inhibits RANKL-induced osteoclastgenesis and function by inhibiting ERK, AKT, JNK, and p38 cascade, following by the c-fos/NFATc1 pathway. Latanoprost acid is a medication which works to lower pressure inside the eyes.

Cat. No.

A95224

CAS No.

171205-17-7

N-Methylquipazine maleate

N-Methylquipazine maleate is a drug derivative that acts as a selective serotonin receptor antagonist. This compound exhibits significant biological activity in modulating neurotransmitter signaling and is utilized in pharmacological research focused on neuropsychiatric disorders. Its properties make it a valuable tool for studies exploring the role of serotonin in mood regulation and behavior.

Cat. No.

A95383

CAS No.

125992-09-8

AHR-11797

AHR-11797 is a drug derivative that functions as a potent antagonist of the aryl hydrocarbon receptor (AHR). This compound demonstrates significant inhibition of AHR-mediated signaling pathways, making it valuable for research involving environmental toxicity and immune regulation. AHR-11797 is primarily utilized in studies exploring the roles of AHR in cancer biology, inflammation, and developmental processes.

Cat. No.

A95407

CAS No.

146574-43-8

3-Hydroxy carvedilol

Synonyms: SB 211475; BM 910228

3-Hydroxy carvedilol is a pharmacologically active derivative of carvedilol, primarily acting as a non-selective beta-blocker and alpha-1 blocker. It exhibits significant cardiovascular effects, including antihypertensive and antianginal properties, making it relevant for studies on cardiovascular diseases. Research applications include the evaluation of its potential in modulating blood pressure and heart rate, as well as its role in vascular function and cardiac protection.

Cat. No.

A95408

CAS No.

148702-58-3

5-HT4 antagonist 3

5-HT4 antagonist 3 is a selective antagonist of the 5-HT4 serotonin receptor, primarily involved in neurotransmission modulation. This compound has demonstrated significant potential in research applications related to neuropharmacology, particularly in studying cognitive function and gastrointestinal motility. Its ability to inhibit 5-HT4 receptor activity makes it a valuable tool for elucidating receptor signaling pathways and developing therapeutic strategies for related disorders.

Cat. No.

A95445

CAS No.

872428-47-2

M-5MPEP

M-5MPEP is a potent metabotropic glutamate receptor 5 (mGluR5) antagonist. It exhibits significant neuroprotective effects and is utilized in research focused on neurological disorders, such as anxiety and depression. This compound provides valuable insights into the modulation of glutamate signaling pathways, making it an important tool for studying synaptic transmission and neuropharmacology.

Cat. No.

A95468

CAS No.

137882-98-5

Abitesartan

Synonyms: CGP-49870

Abitesartan is a drug derivative that functions primarily as an angiotensin II receptor antagonist. It exhibits significant activity in modulating blood pressure and provides valuable insights into cardiovascular research. This compound is utilized in the investigation of hypertension and related disorders, contributing to the development of therapeutic strategies targeting the renin-angiotensin system.

Cat. No.

A95641

CAS No.

2231302-46-6

5-HT4R agonist-1

5-HT4R agonist-1 is a selective agonist for the 5-hydroxytryptamine 4 receptor (5-HT4R), a target involved in various neuropharmacological processes. This compound exhibits significant biological activity in modulating gastrointestinal motility and cognitive functions. It serves as a valuable tool in research applications focused on gastrointestinal disorders and neurodegenerative diseases, aiding in the exploration of therapeutic strategies targeting the serotonergic system.

Cat. No.

A95940

CAS No.

512784-94-0

SRX251

SRX251 is a drug derivative that acts primarily as a serotonin receptor antagonist. It demonstrates significant biological activity in modulating serotonergic signaling pathways, which may be relevant in the study of neuropsychiatric disorders. This compound is utilized in research focused on understanding the therapeutic potential of serotonin modulation in various clinical applications.

Cat. No.

A96213

CAS No.

150351-87-4

GR 100679

GR 100679 is a drug derivative that acts as a selective antagonist. This compound exhibits significant biological activity in modulating receptor interactions, making it valuable for research in pharmacology and drug discovery. Its applications may include studying receptor signaling pathways and assessing therapeutic potential in various disease models.

Cat. No.

A96372

CAS No.

2803608-05-9

STING agonist-49-CO-C2-mal-Cys

STING agonist-49-CO-C2-mal-Cys is a derivative of the STING agonist designed to facilitate the catabolism of antibody-drug conjugates (ADCs) and promote payload release. This compound exhibits significant antitumor activity in vivo, making it a valuable tool in cancer research. Its unique structure provides essential interactions with target proteins and E3 ligases, contributing to its efficacy in therapeutic applications.

Cat. No.

A96413

CAS No.

65934-61-4

RU 24926

RU 24926 is a drug derivative that functions primarily as a selective agonist for the corticotropin-releasing hormone receptor 1 (CRHR1). This compound exhibits key biological activity in modulating stress responses and has been utilized in research related to anxiety and depression models. RU 24926 serves as an important tool for investigating the pathways involved in neuroendocrine regulation and stress-related disorders.

Cat. No.

A96515

CAS No.

845555-94-4

MNI-D-aspartate

MNI-D-aspartate is a potent drug derivative that acts as an NMDA receptor agonist. It plays a critical role in neurotransmission and is vital for studies related to excitatory signaling in the central nervous system. Research applications include investigations into neuropharmacology and the modulation of synaptic plasticity, making it valuable for understanding various neurological conditions.

Cat. No.

A96620

CAS No.

117423-95-7

LTB4 antagonist 4

LTB4 antagonist 4 is a selective antagonist of leukotriene B4 (LTB4), a potent mediator of inflammation. This compound is designed to inhibit LTB4 signaling, potentially reducing inflammatory responses and associated pathologies. It is valuable for research applications related to inflammation, immune responses, and related pharmacological studies.

Cat. No.

A97017

CAS No.

222529-89-7

LY389795

LY389795 is a potent drug derivative that functions as a selective antagonist for specific neurotransmitter receptors. This compound exhibits significant biological activity in modulating neuronal signaling pathways, making it a valuable tool for research in neuropharmacology and drug discovery. Its targeted mechanism supports investigations into various neurological conditions and the development of potential therapeutic agents.

Cat. No.

A97044

CAS No.

56583-56-3

Chinotilin iodide

Chinotilin iodide is a drug derivative that functions as an antagonist in muscle relaxation pathways. It exhibits significant biological activity by inhibiting neurotransmitter release at the neuromuscular junction, contributing to its muscle-relaxing effects. This compound is utilized in research applications focusing on neuromuscular disorders and exploring potential therapeutic interventions for muscular spasms.

Cat. No.

A97081

CAS No.

2177263-88-4

N-Boc norketamine

N-Boc norketamine is an arylcyclohexylamine derivative that acts primarily as a NMDA receptor antagonist. This compound exhibits significant potential in drug discovery and development, particularly in the investigation of neuropharmacological properties and the modulation of depressive-like behaviors. Its applications extend to studies of anesthetic and analgesic mechanisms, providing valuable insights into treatments for mood disorders.

Cat. No.

A97088

CAS No.

98537-38-3

β-Methoxy 2C-D hydrochloride

β-Methoxy 2C-D hydrochloride is a phenethylamine derivative that functions primarily as a selective serotonin receptor agonist. This compound exhibits psychoactive properties and has potential applications in neuroscience research, particularly in the study of serotonin modulation and its effects on behavior. β-Methoxy 2C-D hydrochloride serves as a valuable tool for investigating the pharmacological profiles of serotonin receptor activity and related signaling pathways.

Cat. No.

A97362

CAS No.

1934-55-0

PCPr hydrochloride

PCPr hydrochloride is a derivative of phencyclidine, functioning primarily as an NMDA receptor antagonist. This compound exhibits significant neuropharmacological activity, making it a valuable tool for investigating mechanisms of action in neurotransmission and synaptic plasticity. Research applications include studies on the modulation of excitatory neurotransmitter pathways and the exploration of potential implications in neurodevelopmental and psychiatric disorders.