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Drug Derivative

Drug derivatives are analogs, stereoisomers, esters and conjugates based on known drugs or natural products. C5 Lenalidomide is a variant of lenalidomide, a ligand of the E3 ubiquitin ligase substrate receptor cereblon. The stereoisomers (1R,9S)-Exatecan and (9R)-Exatecan relate to exatecan, a camptothecin-derived topoisomerase I inhibitor. rel-Latanoprost acid corresponds to the free acid of latanoprost, a prostaglandin F2α analog, with relative stereochemistry. Natural product esters are also included, such as cycloartenyl ferulate, an ester of ferulic acid with the triterpenoid alcohol cycloartenol. These compounds support structure-activity studies, comparisons between stereoisomers and the design of conjugates. Precursors used earlier in a synthesis route are listed under Drug Intermediate.

Cat. No.

A72849

CAS No.

564-87-4

11-cis-Retinal

Synonyms: 11-cis Retinaldehyde; 11-cis Vitamin A aldehyde

11-cis-Retinal is an oxidized derivative of 11-cis-Retinol that acts as an inverse agonist by binding to opsin in the mammalian visual system, stabilizing the inactive conformation of rhodopsin. This compound is essential for vision and is involved in growth and development processes. Research indicates that 11-cis-Retinal can restore visual function in moths with impaired vision and has demonstrated the ability to recover retinal function in a mouse model of early-age Leber congenital amaurosis type 2 (LCA2) retinal degeneration.

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0.5 mg

$735.00

2 mg

$13,780.00

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Drug Derivative

11-cis-Retinal