Drug Intermediate

Drug intermediates are building blocks and reagents used to synthesize active compounds and their analogs. The category covers small aromatic ketones and acids, aliphatic keto acids, sugars and amino acid-related compounds. 2'-Hydroxyacetophenone, an ortho-substituted aromatic ketone, is a common precursor of chromones and flavonoids. Phenylglyoxylic acid carries an α-keto acid group on a benzene ring, while levulinic acid is a biomass-derived keto acid used as a platform chemical. Carbohydrate intermediates include DL-Xylose and N-acetyl-D-mannosamine, a biosynthetic precursor of sialic acids. Several entries are also endogenous metabolites or salts, so they serve biochemical as well as synthetic work. Compounds built by modifying an existing drug structure are listed under Drug Derivative.