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Ovalicin

Name: Ovalicin
Brand: Adooq Bioscience
SKU: B19080
Availability: OutOfStock

Cat. No. B19080 CAS 19683-98-8

TRPV1 Inhibitor

Ovalicin is a selective inhibitor of the transient receptor potential vanilloid 1 (TRPV1), exhibiting significant anti-inflammatory and anti-atopic dermatitis effects. It covalently binds to MetAP2, inhibiting its activity and demonstrating efficacy against pathogens such as Enterocytozoon bieneusi. Through the attenuation of LPS-induced calcium influx and modulation of inflammatory gene expression, Ovalicin effectively reduces macrophage and mast cell infiltration in the skin, alleviating allergic symptoms in mouse models. This compound is valuable for research into microsporidiosis and atopic dermatitis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	19683-98-8
Applications	TRPV1 Inhibitor
Formula	C₁₆H₂₄O₅
Molecular Weight	296.36
SMILES	O[C@@]([C@@H]1OC)([C@]([C@H]2C/C=C(C)\C)(O2)C)[C@]3(CCC1=O)CO3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.