Fig. 1 · Structure
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p-NH2-Bn-DOTA
BFC
p-NH2-Bn-DOTA is a bifunctional chelator (BFC) and a macrocyclic derivative of DOTA, designed for tumor pre-targeting applications. This compound facilitates the conjugation of peptides and radionuclides, enabling efficient delivery systems in targeted radiotherapy. Its ability to form stable complexes enhances its utility in various biological research applications, particularly in the field of cancer treatment and diagnosis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 181065-46-3 |
| Applications | BFC |
| Formula | C23H35N5O8 |
| Molecular Weight | 509.55 |
| SMILES | OC(CN(CCN(CCN(CCN(C1)CC(O)=O)CC(O)=O)CC(O)=O)[C@H]1CC2=CC=C(C=C2)N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.