Fig. 1 · Structure

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P300-IN-1

p300 Inhibitor

P300-IN-1 is a selective inhibitor of the histone acetyltransferase p300. This compound interferes with p300-mediated acetylation of histones and non-histone proteins, affecting gene expression and cellular processes. P300-IN-1 is primarily utilized in epigenetics research and studies related to cancer biology, where modulation of acetylation pathways plays a critical role in tumorigenesis and cell differentiation.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2488868-36-4
Applications p300 Inhibitor
Formula C26H25F3N4O5
Molecular Weight 530.50
SMILES
O=C(NC)NC1=CC2=C([C@]3(OC(N(CC(N4[C@@H](C)CC[C@H]4C5=CC(F)=C(F)C(F)=C5)=O)C3=O)=O)CC2)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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