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p97-IN-1

p97 Inhibitor

p97-IN-1 is a potent inhibitor of the p97/valosin-containing protein (VCP), exhibiting an IC50 of 26 nM. This compound significantly impedes the proliferation of tumor cells, making it a valuable tool in cancer research. p97-IN-1 is particularly relevant for studies focused on acute myeloid leukemia (AML) and other malignancies driven by dysregulated protein degradation pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3007658-96-7
Applications	p97 Inhibitor
Formula	C₂₅H₂₆N₆O₂
Molecular Weight	442.51
SMILES	CONC(C1=CC=CC2=C1C=C(N2C3=NC4=C(C(NCC5=CC=CC=C5)=N3)CCCN4)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.