Paclitaxel (Taxol)

Catalog No.: A10689

Microtubule Associated inhibitor

Paclitaxel (Taxol) Chemical Structure

CAS NO. 33069-62-4

Paclitaxel (Taxol) is a mitotic inhibitor that stabilizes microtubules and as a result, interferes with the normal breakdown of microtubules during cell division.

Availability: In stock

Package Price Qty
10 mg
$30.00
50 mg
$50.00
100 mg
$80.00
200 mg
$100.00
10mM * 1mL in DMSO
$50.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Paclitaxel (Taxol) is a mitotic inhibitor that stabilizes microtubules and as a result, interferes with the normal breakdown of microtubules during cell division.
Targets
Microtubule (human endothelial cells)
0.1 pM
In vitro (25°C) DMSO 171 mg/mL (200.25 mM)
Water <1 mg/mL (<1 mM)
Ethanol 18 mg/mL (21.07 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 11.71 mL 58.55 mL 117.11 mL
0.5 mM 2.34 mL 11.71 mL 23.42 mL
1 mM 1.17 mL 5.86 mL 11.71 mL
5 mM 0.23 mL 1.17 mL 2.34 mL

*The above data is based on the productmolecular weight 853.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10689
Actions Inhibitor
M. Wt 853.9
Formula C47H51NO14
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 33069-62-4
Synonyms Taxol
SMILES CC1=C2[[email protected]](C(=O)[[email protected]@]3([[email protected]](C[[email protected]@H]4[[email protected]]([[email protected]]3[[email protected]@H]([[email protected]@](C2(C)C)(C[[email protected]@H]1OC(=O)[[email protected]@H]([[email protected]](C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C

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