PAK4-IN-2

Catalog No.: A30655
PAK4 Inhibitor
PAK4-IN-2 is a potent inhibitor of the p21-activated kinase 4 (PAK4), exhibiting an IC50 value of 2.7 nM. This compound effectively induces cell cycle arrest at the G0/G1 phase and promotes apoptosis in MV4-11 cancer cells. PAK4-IN-2 is suitable for investigations into cancer biology and therapeutic development targeting PAK4 signaling pathways.
Grouped product items
Size Price Stock Qty
1mg
$60.00
In stock
5mg
$155.00
In stock
10mg
$260.00
In stock
25mg
$525.00
In stock
50mg
$810.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPAK4-IN-2 is a potent inhibitor of the p21-activated kinase 4 (PAK4), exhibiting an IC50 value of 2.7 nM. This compound effectively induces cell cycle arrest at the G0/G1 phase and promotes apoptosis in MV4-11 cancer cells. PAK4-IN-2 is suitable for investigations into cancer biology and therapeutic development targeting PAK4 signaling pathways.
Product Information
Catalog NumA30655
FormulaC18H21ClN6
Molecular Weight356.85
CAS Number2488706-33-6
SMILESClC1=CC(NC2=NC(N[C@H]3CC[C@@H](N)CC3)=C4C(NC=C4)=N2)=CC=C1
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