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Pam3CSK4

Catalog No.: A35359
TLR1/2 Agonist
Pam3CSK4 is a potent agonist of toll-like receptors 1 and 2 (TLR1/2), exhibiting an EC50 of 0.47 ng/mL for human TLR1/2 activation. This compound is instrumental in stimulating innate immune responses, making it a valuable tool for research in immunology and related fields. Its application is pivotal in studies aimed at understanding pathogen recognition and the subsequent activation of immune pathways.
Pam3CSK4 112208-00-1 TLR1/2 Agonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPam3CSK4 is a potent agonist of toll-like receptors 1 and 2 (TLR1/2), exhibiting an EC50 of 0.47 ng/mL for human TLR1/2 activation. This compound is instrumental in stimulating innate immune responses, making it a valuable tool for research in immunology and related fields. Its application is pivotal in studies aimed at understanding pathogen recognition and the subsequent activation of immune pathways.
Product Information
Catalog NumA35359
FormulaC81H156N10O13S
Molecular Weight1510.23
CAS Number112208-00-1
SMILES[C@@H](NC([C@@H](NC([C@@H](NC([C@H](CSCC(COC(CCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCC)=O)NC(CCCCCCCCCCCCCCC)=O)=O)CO)=O)CCCCN)=O)(C(N[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CCCCN)=O)CCCCN
SynonymsPam3Cys-Ser-(Lys)4
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Immunology & Inflammation > Toll-like Receptors