Fig. 1 · Structure
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Pamaquine
Antimalarial Agent
Pamaquine is an 8-aminoquinoline compound that functions as an antimalarial agent by targeting Plasmodium species responsible for malaria. Research indicates that while effective in combating malaria, Pamaquine is associated with neurotoxicity and potential damage to specific neuro-anatomical structures, resulting in neurological deficits observed in Rhesus monkey models. This compound is valuable for studies investigating the neurotoxic effects of antimalarial treatments and the mechanisms underlying such adverse effects.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 491-92-9 |
| Applications | Antimalarial Agent |
| Formula | C19H29N3O |
| Molecular Weight | 315.45 |
| SMILES | CC(NC1=C2N=CC=CC2=CC(OC)=C1)CCCN(CC)CC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.