Fig. 1 · Structure
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Panamesine
Sigma Ligand
Panamesine is a selective sigma receptor ligand with a high affinity of IC50 6 nM for sigma binding sites. This compound exhibits potential as an atypical neuroleptic agent, making it of interest in neuropharmacological research. Its unique binding properties may provide insights into the therapeutic mechanisms of sigma receptor modulation in various neurological disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 139225-22-2 |
| Applications | Sigma Ligand |
| Formula | C23H26N2O6 |
| Molecular Weight | 426.46 |
| Synonyms | EMD 57445 |
| SMILES | O=C1O[C@@H](CN2CCC(O)(C3=CC=C(OCO4)C4=C3)CC2)CN1C5=CC=C(OC)C=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.