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Panowamycin A

Antitrypanosomal Agent

Panowamycin A is an isochroman compound primarily targeting the Trypanosoma brucei brucei parasite. It demonstrates significant antitrypanosomal activity, with an IC50 of 0.40 μg/mL, while exhibiting low cytotoxicity towards human fetal lung fibroblast MRC-5 cells (IC50: 2.95 μg/mL). This compound is valuable for research applications focused on antitrypanosomal studies and the development of new therapeutic strategies against trypanosomiasis.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1375224-55-7
Applications	Antitrypanosomal Agent
Formula	C₁₇H₂₄O₃
Molecular Weight	276.37
SMILES	OCC[C@H]1C2=CC(C)=CC=C2[C@@H]([C@](O1)([H])[C@H](C)C(C)=O)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.