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Panowamycin B

Antitrypanosomal Agent

Panowamycin B is an isochroman compound with potent antitrypanosomal activity, specifically targeting the Trypanosoma brucei brucei GUTat 3.1 strain (IC50: 3.30 μg/mL). This compound demonstrates weak cytotoxicity in human fetal lung fibroblast MRC-5 cells (IC50: 13 μg/mL), indicating a favorable safety profile for potential therapeutic applications. Panowamycin B serves as a valuable reagent for research in antitrypanosomal studies and drug development.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1375224-56-8
Applications	Antitrypanosomal Agent
Formula	C₁₇H₂₆O₃
Molecular Weight	278.39
SMILES	OCC[C@@H]1C2=CC(C)=CC=C2[C@@H]([C@](O1)([H])[C@H](C)[C@@H](O)C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.