Fig. 1 · Structure
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Paroxetine
Serotonin Reuptake Inhibitor
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) known for its primary mechanism of blocking serotonin reabsorption in the presynaptic neuron. This compound exhibits significant antidepressant and anti-anxiety properties, making it effective in treating conditions such as obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, and premenstrual anxiety. Additionally, Paroxetine demonstrates a weak norepinephrine reuptake inhibition, with potential anti-tumor activity and the ability to induce cell apoptosis, contributing to its diverse applications in neurological and oncological research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 61869-08-7 |
| Applications | Serotonin Reuptake Inhibitor |
| Formula | C19H20FNO3 |
| Molecular Weight | 329.37 |
| Synonyms | BRL29060 |
| SMILES | FC1=CC=C(C=C1)[C@H]2[C@@H](CNCC2)COC3=CC=C4OCOC4=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.