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Parsatuzumab
Parsatuzumab (Anti-EGFL7; RG 7414) is a humanized monoclonal antibody designed to function as an immunomodulator by targeting and binding to the epidermal growth factor-like domain 7 (EGFL7). This antibody selectively inhibits the interaction between EGFL7 and endothelial cells, which may impede vascular regrowth and modulate the effects of vascular endothelial growth factor (VEGF) inhibition. Parsatuzumab is primarily researched for its potential applications in the regulation of angiogenesis and tumor microenvironment modulation.
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Biological Activity
Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1312797-14-0 |
| Molecular Weight | 148220 |
| Synonyms | Anti-EGFL7; RG 7414 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.