Fig. 1 · Structure
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PAT1inh-B01
SLC26A6 Inhibitor
PAT1inh-B01 is a selective inhibitor of the SLC26A6 transporter, which functions as a Cl-/HCO3- exchanger. With an IC50 of 350 nM, PAT1inh-B01 effectively inhibits anion exchange mediated by PAT1, thereby blocking fluid absorption in the small intestine. This compound is valuable for research focused on small intestinal hyposecretory disorders and related gastrointestinal functions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1775330-54-5 |
| Applications | SLC26A6 Inhibitor |
| Formula | C22H18BrF3N6O2 |
| Molecular Weight | 535.32 |
| SMILES | O=C1C2=C(CCN(C2)C(CN3N=C(C(F)(F)F)C(Br)=C3C)=O)N=C4C=C(C5=CC=CC=C5)NN14 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.