Fig. 1 · Structure

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PC-Biotin-PEG4-NHS carbonate

PROTAC Linker

PC-Biotin-PEG4-NHS carbonate is a PEG-based linker designed for use in the synthesis of PROTACs. This compound functions as a bifunctional reagent to facilitate the conjugation of biotin to target proteins. Its utility in PROTAC development enables researchers to enhance protein degradation pathways for the study of cellular processes and disease mechanisms. This linker is essential for applications in targeted protein degradation and therapeutic research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2055198-03-1
Applications PROTAC Linker
Formula C35H50N6O14S
Molecular Weight 810.87
SMILES
O=C1N[C@]2(CS[C@H]([C@]2(N1)[H])CCCCC(NCCOCCOCCOCCOCCC(NCC3=CC(C(OC(ON4C(CCC4=O)=O)=O)C)=C([N+]([O-])=O)C=C3)=O)=O)[H]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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