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PD 135158

Catalog No.: A59685
CCKB Antagonist
PD 135158 is a selective antagonist of the CCKB receptor, exhibiting an IC50 of 2.8 nM in mouse cortex assays. This compound demonstrates notable anxiolytic properties, making it a valuable tool for research into anxiety disorders and related neuropharmacological studies. Its specificity and potency make PD 135158 suitable for investigating the role of CCKB receptors in various biological contexts.
PD 135158 130325-35-8 CCKB Antagonist
Grouped product items
Size Price Stock Qty
25mg
$2,035.00
In stock
50mg
$2,610.00
In stock
100mg
$3,440.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPD 135158 is a selective antagonist of the CCKB receptor, exhibiting an IC50 of 2.8 nM in mouse cortex assays. This compound demonstrates notable anxiolytic properties, making it a valuable tool for research into anxiety disorders and related neuropharmacological studies. Its specificity and potency make PD 135158 suitable for investigating the role of CCKB receptors in various biological contexts.
Product Information
Catalog NumA59685
FormulaC42H61N5O11
Molecular Weight811.96
CAS Number130325-35-8
SMILESC[C@@](C1(C)C)(CC[C@@]1([H])C2)[C@@H]2OC(N[C@](C(NC[C@@H](C3=CC=CC=C3)NC(CCC(O)=O)=O)=O)(C)CC4=CNC5=CC=CC=C45)=O.O[C@H]([C@@H](O)CNC)[C@H](O)[C@H](O)CO
SynonymsCAM 1028
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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GPCR/G Protein > CCK