PD-161182

Catalog No.: A62100
NK-3 Antagonist
PD-161182 is a non-peptide antagonist targeting the neurokinin-3 (NK-3) receptor. It exhibits potential activity in modulating NK-3 receptor-related pathways, making it a valuable tool for studying various central nervous system disturbances, as well as pain, inflammation, and diseases affecting the pulmonary and skin systems. This compound is essential for researchers exploring the therapeutic implications of NK-3 antagonism in these contexts.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPD-161182 is a non-peptide antagonist targeting the neurokinin-3 (NK-3) receptor. It exhibits potential activity in modulating NK-3 receptor-related pathways, making it a valuable tool for studying various central nervous system disturbances, as well as pain, inflammation, and diseases affecting the pulmonary and skin systems. This compound is essential for researchers exploring the therapeutic implications of NK-3 antagonism in these contexts.
Product Information
Catalog NumA62100
FormulaC29H40F2N4O4
Molecular Weight546.65
CAS Number168570-35-2
SMILESO=C(N[C@](C)(C(NCCCCCCCNC(N)=O)=O)CC1=CC=CC(F)=C1F)O[C@@H](C(C)C)C2=CC=CC=C2
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