PDP-C1-Ph-Val-Cit

Catalog No.: A43197
ADC Linker
PDP-C1-Ph-Val-Cit is a cleavable linker specifically designed for antibody-drug conjugates (ADCs). This compound facilitates the selective release of cytotoxic agents in targeted cancer therapy, enhancing the efficacy of ADCs while minimizing off-target effects. Its unique structure allows for stable attachment to antibodies while ensuring effective drug release in the tumor microenvironment, making it a valuable tool in cancer research and therapeutic development.
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Size Stock
5mg
10mg
50mg
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Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPDP-C1-Ph-Val-Cit is a cleavable linker specifically designed for antibody-drug conjugates (ADCs). This compound facilitates the selective release of cytotoxic agents in targeted cancer therapy, enhancing the efficacy of ADCs while minimizing off-target effects. Its unique structure allows for stable attachment to antibodies while ensuring effective drug release in the tumor microenvironment, making it a valuable tool in cancer research and therapeutic development.
Product Information
Catalog NumA43197
FormulaC26H37N7O5S2
Molecular Weight591.75
CAS Number1610769-13-5
SMILESO=C(N)[C@H](CCCNC(N)=O)N(C([C@H](C(C)C)N)=O)C1=CC=C(COC(NCCSSC2=NC=CC=C2)=O)C=C1
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