PEG12-Tos is a non-cleavable linker utilized in the synthesis of antibody-drug conjugates (ADCs). This PEG-based linker facilitates the construction of stable ADCs, improving the therapeutic efficacy of the conjugated drug while minimizing off-target effects. In addition, PEG12-Tos serves as a versatile linker in the development of PROTACs, enhancing cell permeability and solubility, and expanding research applications in targeted protein degradation and therapeutic interventions.
PEG12-Tos is a non-cleavable linker utilized in the synthesis of antibody-drug conjugates (ADCs). This PEG-based linker facilitates the construction of stable ADCs, improving the therapeutic efficacy of the conjugated drug while minimizing off-target effects. In addition, PEG12-Tos serves as a versatile linker in the development of PROTACs, enhancing cell permeability and solubility, and expanding research applications in targeted protein degradation and therapeutic interventions.
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